Chief of Staff, Senior Director Global Regulatory Affairs at AstraZeneca

Chief of Staff, Senior Director Global Regulatory AffairsThe Chief of Staff (CoS) serves as a strategic partner to the VP, Head of Global Regulatory Affairs, enabling effective leadership, decision making, execution, and communication across Global Regulatory Affairs at Alexion.Introduction to role: The role acts as an extension of the VP, ensuring alignment between strategy and execution, optimizing governance and leadership forums, and driving cross functional coordination at enterprise level.This role combines strategic advisory, operational leadership, and executive facilitation, with a strong focus on prioritization, organizational effectiveness, and delivery of strategic objectives. Accountabilities:Strategic Partnership and Advisory: Act as a trusted advisor to the VP on strategic, organizational, and operational matters; translate priorities into actionable plans; provide independent challenge to improve decisions and outcomes.Leadership Governance and Operating Rhythm: Own and optimize leadership governance and interfaces; shape agendas and decision frameworks; ensure decisions have clear owners, timelines, and follow-through that advances portfolio progress.Business Planning and Performance Management: Lead annual and multi-year planning; align objectives, KPIs, and resource plans with enterprise strategy; surface risks, trade-offs, and escalation points early to protect timelines and quality.Cross-Functional and Enterprise Coordination: Partner across R&D, Commercial, Safety, Medical, Legal, Finance, and Procurement to align competing priorities; coordinate across programs, therapy areas, and regions to resolve complex issues that impact filing readiness and approvals.Organizational Effectiveness and Change: Support organization design, capability building, and talent initiatives; lead change programs and improvements in ways of working that increase clarity, speed, and accountability across the regulatory organization.Executive Office and Communications: Run the Regulatory Affairs Executive Office; craft executive materials and narratives that drive decisions; represent the VP in internal forums to maintain momentum and continuity on critical deliverables.Essential Skills/Experience:At least 10+ years experience in Regulatory Affairs, R&D, or closely related functions within a global organizationProven experience supporting senior executives or leadership teamsStrong understanding of drug development, regulatory strategy, and governance modelsExperience operating in a matrixed, global environmentAdvanced degree in life sciences, regulatory affairs, or related discipline preferredStrategic thinking with the ability to translate strategy into executionStrong judgment and discretion in handling confidential and sensitive mattersExceptional stakeholder management and influencing skills across senior levelsLeadership facilitation and decision framingOperational rigor with comfort managing ambiguity and complexityChange leadership and organizational effectiveness mindsetExcellent written and verbal communicationThe annual base pay for this position ranges from $218,058.40 -$327,087 USD. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles).Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.When we put unexpected teams in the same room, we fuel ambitious thinking with the power to encourage life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our outstanding and ambitious world.Date Posted13-Jul-2026Closing Date23-Jul-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.SummaryLocation: US - Boston - MAType: Full time