Director, Protein Therapeutics at Vertex Pharmaceuticals

Job DescriptionDirector Protein TherapeuticsJob DescriptionGeneral Summary:Vertex is seeking an accomplished and highly skilled scientific leader to join our Protein Therapeutics team in Seattle. This role will be critical in advancing our pipeline of innovative biologics from early development to clinical readiness in a dynamic fast-paced and highly collaborative environment. The ideal candidate will leverage deep scientific expertise strong leadership and mentorship skills and strategic vision to deliver transformational protein-based therapeutics for diseases with serious unmet medical need.Key Duties & Responsibilities Provide strategic leadership and scientific direction for a team specializing in protein engineering and production while fostering a culture of scientific rigor professional growth and a collaborative work environment. Direct purification and analytical characterization of diverse biologics modalities including Fc fusions monoclonal or bispecific antibodies and novel protein formats. Identify and implement emerging technologies (e.g. computational design high-throughput screening) to accelerate development timelines. Identify evaluate and manage CRO/CMOs for antibody discovery campaigns protein engineering and production. Contribute to cross-functional and cross-site project teams ensuring alignment with internal and external stakeholders to execute on research programs deliver results and influence decision making.Required Education LevelPh.D. in Biochemistry Biomedical Engineering Molecular Biology or a related discipline with a minimum of 10 years of research experience in a biotechnology or pharmaceutical setting is required.Required Knowledge/Skills Ability to lead a diverse team of high-performing scientists focused on protein engineering and protein purification. Proven track record in therapeutic antibody discovery and optimization including antibody screening engineering and developability assessment. Deep expertise with diverse biophysical and bioanalytical techniques such as SPR/BLI DLS thermal stability and aggregation assays. Experience with computational protein modeling or developing AI/ML pipelines is highly desired. Demonstrated ability to design analyze and interpret complex data sets with exceptional attention to detail and scientific rigor. Experience managing antibody discovery campaigns with CROs is highly desirable. Strong record of scientific innovation and impact supported by patents and/or peer-reviewed publications. Excellent communication and interpersonal skills with the ability to clearly present experimental results and recommendations to cross-functional teams leadership and external collaborators. Highly motivated collaborative and adaptable with a passion for advancing breakthrough protein therapeutics in a fast-paced multidisciplinary environment.#LI-KM4Pay Range:$188800 - $283200Disclosure Statement:The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors including skills competencies experience and other job-related factors permitted by law.At Vertex our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career financial family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter) educational assistance programs including student loan repayment a generous commuting subsidy matching charitable donations 401(k) and so much more.Flex Designation:On-Site DesignatedFlex Eligibility Status:In this On-Site designated role you will work five days per week on-site with ad hoc flexibility.Note: The Flex status for this position is subject to Vertexs Policy on Flex @ Vertex Program and may be changed at any time.#LI-OnsiteCompany InformationVertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race color sex gender identity or expression age religion national origin ancestry ethnicity disability veteran status genetic information sexual orientation marital status or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager or contact Talent Acquisition at Required Experience:Director Key Skills Fundraising,Management Experience,Coaching,Analysis Skills,Strategic Planning,Team Management,Budgeting,Leadership Experience,Mentoring,Public Speaking,negotiation,Supervising Experience Employment Type : Full-Time Experience: years Vacancy: 1 Monthly Salary Salary: 188800 - 283200