Research Fellow-Neuroscience-Rossoll Lab for Translational Neuroproteomics at Mayo Clinic

DescriptionThe Rossoll Labat Mayo Clinic Floridais recruiting a Postdoctoral Fellowto join an NIH-funded project exploring the molecular chaperone functions of nuclear-import receptor proteins (importins)in frontotemporal dementia (FTD)and amyotrophic lateral sclerosis (ALS). Our goal is to understand how importin act as chaperons to regulate TDP-43 phase behavior nuclear import and toxicity and how these mechanisms can be harnessed to design therapeutic strategies for TDP-43 proteinopathies.We use a multidisciplinary approach combining molecular and cell biology advanced fluorescence microscopy proteomics and mouse modelsof neurodegenerative disease to uncover how importin-mediated pathways maintain neuronal proteostasis.The position offers an opportunity to work in a highly interactive neuroscience community at Mayo Clinic Florida with access to world-class facilities and other resources including the brain bank.A Research Fellow position in Life Sciences (LS) will require knowledge of either clinical-based research or laboratory-based research often obtained from a postdoctoral program.A Research Fellow at Mayo Clinic is a temporary position intended to provide training and education in research. Individuals will train in the research program of a Mayo Clinic principal investigator. Qualified individuals will demonstrate the potential for research as evidenced by their training and peer-reviewed publications and should become competitive for national research grants. Proof of English proficiency is required for J-1 Short-Term Scholars Research Scholars Professors Specialists and Student Interns sponsored by Mayo Clinic.QualificationsWe are looking for a candidate who:Ph.D. (or equivalent) in Neuroscience Cell or Molecular Biology Biochemistry or related fieldStrong background in molecular and cell biology techniques mammalian cell culture and fluorescence microscopeExperience with mouse models of neurodegeneration is highly desirableAre creative collaborative and eager to work in an interdisciplinary environmentInterested applicants should send a cover letter CV and contact information for three referencesto Dr. Wilfried Rossoll at.Location: Jacksonville FloridaContact:Dr. Wilfried Rossoll More info: Fellow is appropriate for individuals who have completed no more than one prior postdoctoral fellowship at Mayo Clinic or elsewhere. Key Skills Bioinformatics,Genetics,R,Biochemistry,Cell Biology,Research Experience,Statistical Software,Cell Culture,Molecular Biology,Data Analysis Skills,Flow Cytometry,Microscopy Employment Type : Full-Time Experience: years Vacancy: 1