Senior Scientist, Antibody Discovery & Engineering at Pfizer

Senior Scientist Antibody Discovery & EngineeringJob DescriptionROLE SUMMARY:As a research scientist you will be part of Pfizers Worldwide Research and Development team that employs a multidisciplinary approach to identify cancer targets and develop next generation Oncology therapeutics and therapeutic this role you will contribute to the development of novel biotherapeutics as a molecular biology subject matter expert. You will be responsible for extensive molecular biology design experimentation and analysis including construct design vector cloning and NGS library preparation. You will also contribute to molecular analyses of cancer targets cell line engineering antibody sequencing identification of sequence liabilities and antibody engineering.With your deep knowledge in the discipline you will be an active team member who influences at the project team level. You will be using your scientific judgment to adapt standard methods and techniques by applying prior work experience and consulting others. Your ability to plan will help in preparing short-term work activities on projects. Your creativity in developing novel processes and new ideas will be used frequently. You will undertake mentoring activities to guide your team members. It is your innovative scientific temperament that will help in making Pfizer ready to achieve new milestones and help patients across the globe.ADDITIONAL POINTS:Provide molecular biology and engineering support for multiple Oncology Research projectsGenerate analyze and engineer antibody sequences to deliver an optimized therapeutic leadContribute to achievement of goals and influence at the project team levelEvaluate data and provide clear reports that can be shared and transferred to and from cross-functional teamsPay attention to detail strictly adhere to safety protocols and use knowledge of basic laboratory procedures to advance projects under rapidly shifting priorities and timelinesBASIC QUALIFICATIONS:Ph.D. in Molecular Biology or related discipline or Bachelors degree 9 years research experience or Masters degree 7 years research experienceExperience working with antibody sequences including diversity analysis liability identification and CDR annotationMolecular biology skills including RNA/DNA extractions primer design PCR plasmid cloning and NGS library prepFamiliarity with sequence analysis software such as Snapgene and/or Geneious PrimeUnderstanding of protein structure and biology; working knowledge of online bioinformatics tools to analyze gene mRNA and protein sequences.Demonstrated ability to work independently and collaboratively adapting to project needsAbility to organize and prioritize work to meet timelines and deliverablesStrong written and verbal communication skills including ability to accurately document experiment data and present resultsPREFERRED QUALIFICATIONS:Proficiency in Oxford Nanopore sequencing and data analysisExperience coding in Python R or other programming languageUnderstanding of antibody biology and antibody drug conjugates (ADCs)Experience with cell engineering technologies such as transfection nucleofection lentiviral transduction and CRISPRProficiency in culturing multiple cell lines under BSL2 conditionsExposure to working in the biopharmaceutical industryPassion for identifying and implementing new technologies that improve workflow efficiency and deliverable qualityPHYSICAL/MENTAL REQUIREMENTSLifting sitting standing walking bending ability to perform mathematical calculations and ability to perform complex data analysisMust be able to wear specialized protective clothing and PPE (lab coat safety shoes/glasses/etc)Additional Information: Work Location Assignment:On PremiseRelocation Support AvailableLast Day to Apply: January 5 2026The annual base salary for this position ranges from $90900.00 to $151500.00. In addition this position is eligible for participation in Pfizers Global Performance Plan with a bonus target of 12.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of lifes moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution paid vacation holiday and personal days paid caregiver/parental and medical leave and health benefits to include medical prescription drug dental and vision coverage. Learn more at Pfizer Candidate Site U.S. Benefits (). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa FL or any location outside of the United States.Relocation assistance may be available based on business needs and/or eligibility.Sunshine ActPfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care providers name address and the type of payments or other value received generally for public disclosure. Subject to further legal review and statutory or regulatory clarification which Pfizer intends to pursue reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse your name address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter please do not hesitate to contact your Talent Acquisition representative.EEO & Employment EligibilityPfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race color religion sex sexual orientation age gender identity or gender expression national origin disability or veteran status. Pfizer also complies with all applicable national state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. Pfizer endeavors to make to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing please email. This is to be used solely for accommodation requests with respect to the accessibility of our website online application process and/or interviewing. Requests for any other reason will not be returned.Research and DevelopmentRequired Experience:Senior IC Key Skills Laboratory Experience,Mammalian Cell Culture,Biochemistry,Assays,Protein Purification,Research Experience,Next Generation Sequencing,Research & Development,cGMP,Cell Culture,Molecular Biology,Flow Cytometry Employment Type : Full-Time Experience: years Vacancy: 1 Monthly Salary Salary: 90900 - 151500